Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. In the coming years, the burden of AF is expected to grow as the older age groups become more prominent. We will use the Danish nationwide registries and new research methods to examine the disease burden of atrial fibrillation in Denmark. Our primary focus is disease pathways, life years lost, and healthcare costs.
Disease burden of atrial fibrillation: new methods and perspectives
Atrial fibrillation is the most common sustained arrhythmia in clinical practice, with a lifetime risk of 1 in 3. AF is associated with significant morbidity, high mortality, and considerable health expenditures. In the coming years, the burden of atrial fibrillation is likely to grow as the population in high-income countries is undergoing substantial demographic shifts.
To encourage further prevention and to improve the prognosis, quality of care, and patient safety among patients diagnosed with atrial fibrillation by measuring the disease burden of atrial fibrillation. We will use new and advanced epidemiological and biostatistical methods to provide novel and unique perspectives on patients with atrial fibrillation in Denmark.
We will use individual-level linkages between several nationwide data sources to conduct a series of national cohort studies among all individuals in the general Danish population. Statistical models will be used to model complex disease pathways related to atrial fibrillation, examine life years lost to atrial fibrillation, and calculate health care costs associated with atrial fibrillation.
Søren Paaske Johnsen, MD, PhD, Professor and Senior Consultant, Danish Center for Clinical Health Services Research, Aalborg University and Aalborg University Hospital
Ludovic Trinquart, MSc, MPH, PhD, Director and Associate Professor, Tufts Medical Center, Boston, USA
Lars Frost, MD, PhD, DMSc, Associate Professor and Consultant Cardiologist, Diagnostic Centre, Silkeborg Regional Hospital, and Department of Clinical Medicine, Aarhus University
Jan Sørensen, MSc, Director and Professor of Health Economics, RCSI University of Medicine and Health Sciences, Ireland
Emelia J. Benjamin, MD, ScM, Associate Provost, Professor, and Consultant Cardiologist, Boston University School of Medicine and Boston University School of Public Health, Boston, USA